Ramipril (Cardace)

Ramipril is a type of drug called ACE inhibitor. ACE stands for Angiotensin Converting Enzyme. Ramipril works by helping to block an enzyme that normally causes blood vessels to narrow. By blocking this enzyme, ramipril causes blood vessels to relax, which lowers blood pressure. Because of this function, Ramipril is very effective in treating high blood pressure (hypertension), heart failure, and to improve survival rates after a heart attack.

Ramipril - Product Description

How to use

Ramipril should be taken orally once a day with a full glass of water. It can be taken with or without food. Take Ramipril at approximately the same time every day to maintain an even level of the drug in your blood.

Take Ramipril exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Your doctor may occasionally change your dose to make sure you get the best results from this medication.

While you are taking Ramipril, you could experience vomiting, diarrhea or heavy sweating and this can cause you to become dehydrated. That can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking Ramipril. Drink plenty of water each day while you are taking this medication.


Symptoms of a Ramipril overdose may include feeling extremely dizzy or light-headed or fainting. Seek emergency medical attention if you think you have used too much of this medicine.

Missed dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.


Avoid drinking alcohol while taking Ramipril. It can further lower your blood pressure and may increase some of the side effects of Ramipril.
Do not use salt substitutes or potassium supplements while taking Ramipril, unless your doctor has told you to.
Do not share this medication with others, as they may have a problem that is not effectively treated by this drug.

Important note

The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed that the taking of this medication is safe, appropriate or effective for you.

Drug interactions

Before taking Ramipril, tell your doctor if you are taking any of the following drugs:

If you are using any of these drugs, you may not be able to use Ramipril or you may need dosage adjustments or special tests during treatment.

This list is not complete and other drugs may interact with Ramipril. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Ramipril Full Prescribing Information

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You should not use this medication if you are allergic to Ramipril or to any other ACE inhibitor, such as:

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Ramipril:

Ramipril is classed by the FDA as pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Ramipril could cause birth defects in the baby if you take the medication during pregnancy. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Ramipril can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Ramipril:

Call your doctor at once if you have any of these serious side effects:

Less serious Ramipril side effects may include:

Notify your doctor if any other side effects occur, especially if they are specifically bothersome.


How does Ramipril work?

Ramipril belongs to a class of drugs called ACE inhibitors. ACE stands for Angiotensin-Converting Enzyme. Ramipril helps to block these enzymes, which are a normal part of a reaction in the body that causes the blood vessels to narrow (constrict). By blocking this enzyme, it causes blood vessels to relax, which lowers blood pressure. 

ramipril structure

What is the recommended dosage?

The usual dose of Ramipril is 2.5-20 mg a day as a single dose or two divided doses. Patients taking diuretics or who have renal artery stenosis (narrowing of the arteries going to the kidney) may require lower doses.

How long does it take for Ramipril to start working?

Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Ramipril. You must also continue taking Ramipril, even if you are feeling well. Ramipril does not cure high blood pressure, it merely keeps it under control. Remember to take the drug regularly for it to have maximum effect.

Can I drink alcohol while taking Ramipril?

Avoid consuming alcohol when you’re taking Ramipril. Alcohol can lower your blood pressure and may increase some of the side effects of Ramipril.

What should I discuss with my healthcare professional before taking Ramipril?

You should talk with your healthcare provider prior to taking Ramipril if you:

- Have heart disease 
- Have liver failure
- Have kidney disease
- Have diabetes
- Will be undergoing surgery or anesthesia. 

Let your healthcare provider know if you are pregnant or thinking about becoming pregnant. During pregnancy, Ramipril can cause damage or even death to the developing fetus.

Tell your healthcare provider about all the medicines you take (including prescription and non-prescription medicines, vitamins, and herbal supplements), especially if you are taking a diuretic (water pill) or a potassium supplement.

Do not take any salt substitutes containing potassium without first discussing it with your healthcare provider.

Effective for high blood pressure, heart failure and to improve survival rates after heart attack
Reduces the risk of heart attack, stroke, bypass surgery and diabetes in patients with heart disease
Effective for heart disease patients with diabetes and other risk factors, such as smoking or high cholesterol


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